abstract：:A 49-year-old diabetic woman developed polymicrobial anaerobic meningitis secondary to a meningorectal fistula one year after receiving neutron beam therapy for a rectal adenocarcinoma. The meningitis was refractory to chloramphenicol and penicillin but responded to oral metronidazole. Sustained eradication of meningi...

journal_title：American journal of clinical pathology

authors： Walsh TJ,Weinstein RA,Malinoff H,Breyer MD,Berelowitz BA

更新日期：1982-07-01 00:00:00

abstract：:A simple scheme for the speciation of clinical isolates of "viridans" streptococci based on nine physiological characteristics is presented. Use of this scheme will enable successful speciation of most "viridans" strep isolates in any laboratory and allow for the accumulation of data necessary for the definition of cl...

journal_title：American journal of clinical pathology

authors： Sands M,Sommers HM,Rubin MB

更新日期：1982-07-01 00:00:00

abstract：:Plasma samples from patients with severe classic hemophilia, suspected of having mild inhibitors not detected in the standard Bethesda inhibitor test, were examined in modified Bethesda tests and in a screening test based on the activated partial thromboplastin time (APTT). The APTT test was more sensitive to mild inh...

journal_title：American journal of clinical pathology

authors： Ewing NP,Kasper CK

更新日期：1982-06-01 00:00:00

abstract：:In a university-affiliated community hospital, medical records of 58 patients on whom the intact parathyroid hormone immunoassay (I-PTH) and 29 patients on whom both the carboxyl terminal PTH(C-PTH) and I-PTH ordered by physicians were reviewed to determine the reasons for requesting these tests. Reasons for ordering ...

journal_title：American journal of clinical pathology

authors： Juan D,Wehrmeister J

更新日期：1982-06-01 00:00:00

abstract：:Following normalization of blood glucose levels, a marked change in the MCV and in the calculated hematocrit was observed in five patients with transient severe hyperglycemia. The addition of varied concentrations of glucose to blood samples from healthy volunteers and from patients with microcytic, macrocytic, and no...

journal_title：American journal of clinical pathology

authors： Holt JT,DeWandler MJ,Arvan DA

更新日期：1982-05-01 00:00:00

abstract：:A rapid, convenient immunologic assay technic for fibrinogen is reported. Basically a latex agglutination, the assay technic, called kinetic latex agglutinometry, quantitates the increase in light transmission that occurs in a stirred suspension of anti-fibrinogen-coated latex beads after the addition of a plasma or w...

journal_title：American journal of clinical pathology

authors： Babson AL,Opper CA,Crane LJ

更新日期：1982-04-01 00:00:00

abstract：:Terminal transferase (TdT) activity and antigen have been measured in 267 specimens of human bone marrow and peripheral blood by using a biochemical assay for enzymatic activity and an immunofluorescence test for antigen. Oligo p(dA)50 and dGTP were used as reagents in the biochemical assay and either rabbit anti-calf...

journal_title：American journal of clinical pathology

authors： Cibull ML,Coleman MS,Nelson O,Hutton JJ,Gordon D,Bollum FJ

更新日期：1982-04-01 00:00:00

abstract：:The lupus anticoagulant was identified in three patients. Laboratory studies gave evidence of inhibitory activity directed against phospholipid and prekallikrein. Inhibition of prekallikrein has not been reported previously. When exposed to kaolin, all three patients' plasmas failed to develop the level of fibrinolyti...

journal_title：American journal of clinical pathology

authors： Sanfelippo MJ,Drayna CJ

更新日期：1982-03-01 00:00:00

abstract：:A 73-year-old man with myelodysplastic syndrome developed during the course of his illness auto-immune hemolytic anemia. The association between auto-immune hemolysis and myeloproliferative disease is extremely rare. An even more unique finding is the nature of the antibody which demonstrated single specificity agains...

journal_title：American journal of clinical pathology

authors： Sacher RA,McGinniss MM,Shashaty GG,Jacobson RJ,Rath CE

更新日期：1982-03-01 00:00:00

abstract：:Urine cultures represent 40-50% of specimens processed by hospital clinical microbiology laboratories. An accurate rapid screening method to detect positive urine cultures could greatly improve laboratory efficiency. Three hundred eighty-two unselected urines were screened by nephelometry at 2, 4, and 5 hours of shaki...

journal_title：American journal of clinical pathology

authors： Heinz T,Pezzlo M,Thrupp L

更新日期：1982-03-01 00:00:00

abstract：:A patient with an acute burn was noticed to have spuriously elevated platelet counts on an automated system. The major factor accounting for this discrepancy was the presence of numerous microspherocytes which were in the same size range of platelets. It is thus important to add microspherocytosis as an additional cau...

journal_title：American journal of clinical pathology

authors： Akwari AM,Ross DW,Stass SA

更新日期：1982-02-01 00:00:00

abstract：:Terminal deoxynucleotidyl transferase (TdT) is a marker of lymphoblastic disorders. Previously, the technique for determining TdT on smears was by indirect immunofluorescence. An immunoperoxidase procedure for detecting TdT on smears is reported. Results are in a comparable range with the indirect immunofluorescent te...

journal_title：American journal of clinical pathology

authors： Stass SA,Dean L,Peiper SC,Bollum FJ

更新日期：1982-02-01 00:00:00

abstract：:Hyperparathyroidism may occasionally present as a neck mass resulting from cystic change in a parathyroid adenoma. We report an unusual instance of hyperparathyroidism presenting as a palpable, but asymptomatic hyperplastic parathyroid gland cyst. We conclude that hyperplastic parathyroid glands may undergo cystic deg...

journal_title：American journal of clinical pathology

authors： Fallon MD,Haines JW,Teitelbaum SL

更新日期：1982-01-01 00:00:00

abstract：:Vitamin E has been reported to increase serum high-density lipoprotein (HDL) cholesterol. Given the known inverse relationship between HDL-cholesterol and risk of developing coronary artery disease, these preliminary results require verification or refutation. In the present study, 39 volunteers were given 600 U of vi...

journal_title：American journal of clinical pathology

authors： Howard DR,Rundell CA,Batsakis JG

更新日期：1982-01-01 00:00:00

abstract：:The characteristics of the normal adult thymus in both sexes were determined in 50 cases of accidental death by a simplified quantitative histologic technic. A table of normal values derived from these findings was used for making comparisons with thymus from autopsies of 50 additional patients suffering terminal illn...

journal_title：American journal of clinical pathology

authors： Smith SM,Ossa-Gomez LJ

更新日期：1981-11-01 00:00:00

abstract：:The participant performances on the College of American Pathologists (CAP) Urine Survey specimens distributed during 1979 and 1980 for pregnancy testing are reviewed. Almost all the reagent methods used by the participants performed well on the negative specimens. Prominent differences in results on the positive speci...

journal_title：American journal of clinical pathology

authors： Biesecker JL,Rippey JH

更新日期：1981-10-01 00:00:00

abstract：:Two radioimmunoassay procedures (RIA-1 and RIA-2) were evaluated for the quantitation of prostatic acid phosphatase in serum and compared with the enzymatic method and counter immunoelectrophoresis method for their specificity and sensitivity. Sera from 168 patients were analyzed and these included: normals, 27; untre...

journal_title：American journal of clinical pathology

authors： Gupta MK,Rajaraman S,Gupta SK,Hewitt CB,Deodhar SD

更新日期：1981-10-01 00:00:00

abstract：:A 30-year-old previously healthy man developed cervical adenopathy associated with mild constitutional symptoms. Corynebacterium ovis was isolated in pure culture from lymph node tissue on two separate occasions, and small gram positive organisms were identified in both lymph nodes with tissue gram stain. Histopatholo...

journal_title：American journal of clinical pathology

authors： Goldberger AC,Lipsky BA,Plorde JJ

更新日期：1981-10-01 00:00:00

abstract：:An automated fluorescent immunoassay system (FIAX) was compared with complement fixation (CF) for measuring antibodies to cytomegalovirus (CMV) and herpes simplex virus (HSV) in clinical specimens. Compared with CF the specificity of FIAX (ability to detect a negative titer) was 95% for CMV and 92% for HSV. The sensit...

journal_title：American journal of clinical pathology

authors： Friedman HM,Tustin NB,Hitchings MM,Plotkin SA

更新日期：1981-09-01 00:00:00

abstract：:Patients with nonhemolytic Lewis antibodies in the serum were transfused on the basis of major crossmatch compatibility alone. No adverse clinical affects were noted when 33 such patients received a total of 230 transfusions. Considerable savings in technologist time and reagent cost were realized by adopting this pol...

journal_title：American journal of clinical pathology

authors： Waheed A,Kennedy MS,Gerhan S,Senhauser DA

更新日期：1981-09-01 00:00:00

abstract：:This report describes four siblings affected with familial intrahepatic cholestasis detected in early infancy. In the two male siblings, biliary cirrhosis and fatal hepatocellular carcinoma later developed, whereas the female siblings have had persistent hepatomegaly and recurrent episodes of cholestasis. Sequential b...

journal_title：American journal of clinical pathology

authors： Ugarte N,Gonzalez-Crussi F

更新日期：1981-08-01 00:00:00

abstract：:Blood glucose results for 2,601 specimens obtained at multiphasic health examination, divided into three age groups, were analyzed using probability plot paper. Two straight lines could be fitted to each distribution. The assumption was made that the lower lines correspond to "normal-healthy" persons, whereas the uppe...

journal_title：American journal of clinical pathology

authors： Morgenstern NL,Shearn MA

更新日期：1981-08-01 00:00:00

abstract：:The effects of physiologic temperature variations on antibiotic-induced killing of Escherichia coli, Pseudomonas aeruginosa, Streptococcus faecalis, and Streptococcus pneumoniae were studied. At concentrations less than or equal to four times the minimal bactericidal concentration, the activity of each of the antibiot...

journal_title：American journal of clinical pathology

authors： Mackowiak PA,Ruderman AE,Martin RM,Many WJ,Smith JW,Luby JP

更新日期：1981-07-01 00:00:00

abstract：:An unusual case of carcinoma of the prostate with metastases is described. the prostate and the metastases showed adenocarcinoma with carcinoid-like areas. A tumor with the same histologic features was found at the tip of the appendix and proved to be metastatic. The possibility of primary carcinoid of the prostate wa...

journal_title：American journal of clinical pathology

authors： Ansari MA,Pintozzi RL,Choi YS,Ladove RF

更新日期：1981-07-01 00:00:00

abstract：:An American black family in whom hemoglobin J Baltimore and beta (+)-thalassemia genes coexisted is described. The proposita is a 23-year-old woman with a hemoglobin (Hb) level of 11.5 g/dl, microcytic, hypochromic indices, increased values of Hbs A2 and F, and alpha/non-alpha synthetic ratio of 1.52. Hbs A and J Balt...

journal_title：American journal of clinical pathology

authors： Ballas SK,Atwater J,Theriault C,Kim HC,Propst M

更新日期：1981-06-01 00:00:00

abstract：:A ligand assay specific for cobalamin that uses mouse stomach as the source of intrinsic factor has been developed. When mouse stomach extract incubated with radiocobalamin is fractionated by gel chromatography, the radioactive complex elutes as a single peak with apparent molecular weight of 54,900. Formation of the ...

journal_title：American journal of clinical pathology

authors： Reynoso G,Tuggey R,Hansen H,Fontelo PA,Konopka S,Miller JT

更新日期：1981-06-01 00:00:00

abstract：:Thrombocytosis may reflect a primary myeloproliferative disorder or be a secondary reaction to other pathologic processes. Patients with persistent unexplained thrombocytosis meeting criteria of primary thrombocythemia had elevated levels of serum lactic dehydrogenase, whereas comparable patients with secondary thromb...

journal_title：American journal of clinical pathology

authors： Budman DR,Lackner H,Berczeller P,Silber R

更新日期：1981-06-01 00:00:00

abstract：:A structure resembling a sulfur granule found in histologic sections of endometrium from patients with intrauterine contraceptive devices is described. It is distinguished from a true sulfur granule on morphologic grounds and is further characterized as a foreign substance, most probably fragments of the synthetic con...

journal_title：American journal of clinical pathology

authors： O'Brien PK,Roth-Moyo LA,Davis BA

更新日期：1981-06-01 00:00:00

abstract：:A unique case of intramural uterine tumor composed of malignant epithelium and benign smooth muscle, adipose tissue, and cartilage is reported. This tumor, which the authors designated "carcinomesenchymoma," apparently represents an example of a previously unreported variant of mixed müllerian tumor that is composed o...

journal_title：American journal of clinical pathology

authors： Chen KT,Vergon JM

更新日期：1981-05-01 00:00:00

abstract：:A case of metastatic ameloblastoma of the maxilla with secondary hypercalcemia in a 54-year-old man is presented. After treatment with surgery, chemotherapy, and radiotherapy, the patient was found to have multiple metastases and severe hypercalcemia associated with high levels of parathormone-like substance in the pe...

journal_title：American journal of clinical pathology

authors： Madiedo G,Choi H,Kleinman JG

更新日期：1981-04-01 00:00:00

abstract：:Primary malignant germ cell tumors of the mediastinum are extremely rare among females. This report describes such a tumor arising in the mediastinum of a 26-year-old woman and correlates immunohistochemical studies of the neoplasm with serum tumor markers. Microscopic examination of the tumor revealed an embryonal ca...

journal_title：American journal of clinical pathology

authors： Sandhaus L,Strom RL,Mukai K

更新日期：1981-04-01 00:00:00

abstract：:Hepatocytes with orcein-positive ground-glass cytoplasm have been shown to contain abundant hepatitis B surface antigen in the cisternae of excess smooth endoplasmic reticulum. Hepatocytes with similar cytoplasmic changes that did not react with orcein were observed in 26.5% of 49 cases of cirrhosis. These cells exhib...

journal_title：American journal of clinical pathology

authors： Gerber MA,Thung SN

更新日期：1981-04-01 00:00:00

abstract：:A practical acidimetric assay for penicillinase production using penicillin and phenol red impregnated in paper discs was developed. Blank discs were first impregnated with buffered penicillin G and, after drying, with 1% phenol red. For use, a disc was added to a bacterial suspension made in saline solution. A yellow...

journal_title：American journal of clinical pathology

authors： Tu KK,Jorgensen JH,Stratton CW

更新日期：1981-04-01 00:00:00

abstract：:The primary role of the surgical pathologist is to diagnose, and then to transmit this information effectively so that it can be used to guide patient management; therefore, the dual roles of the surgical pathologist as a diagnostician and consultant are inextricable. The diagnostic pathologist determines the nature, ...

journal_title：American journal of clinical pathology

authors： Hutter RV

更新日期：1981-03-01 00:00:00

abstract：:A prospective double-blind trial was performed to investigate the safety of long-term oral anticoagulant control when dosaged adjustment depends on the prothrombin times assessed with one type of thromboplastin being calculated as if assayed by another type. The three main types of thromboplastin, i.e., bovine (Thromb...

journal_title：American journal of clinical pathology

authors： Boekhout-Mussert MJ,van der Kolk-Schaap PJ,Hermans J,Loeliger EA

更新日期：1981-03-01 00:00:00

abstract：:Laboratory Branch Complement Fixation and FIAX (fluorescence immunoassay) were compared for the detection of antibodies to herpes simplex virus and cytomegalovirus in human sera. Of 68 sera with no antibodies to herpes simplex virus by complement fixation, one specimen was positive by FIAX (specificity, 98.6%). Of 75 ...

journal_title：American journal of clinical pathology

authors： Segar JE,Smith TF,Ilstrup DM

更新日期：1981-03-01 00:00:00

abstract：:Because of the unusual presentation of pernicious anemia in many black women, a further characterization of this disease among the different racial groups was undertaken. The following were found. (1) Black women under the age of 50 years had a significantly lower prevalence of anti-parietal cell antibody than did "Eu...

journal_title：American journal of clinical pathology

authors： Carmel R,Ozturk G,Johnson CS,Tung KS,Terasaki PI

更新日期：1981-03-01 00:00:00

abstract：:The Travenol Hem-O-Scan and the Instrumentation Laboratory (IL) system for determination of the oxygen dissociation curve and P50 values have been evaluated. Using the Hem-O-Scan, an oxygen dissociation curve and P50 value may be obtained on 2 microliter of blood in 40 min, though the pH is not measured. In the IL sys...

journal_title：American journal of clinical pathology

authors： Nelson MG,Savage GA,Cooke PJ,Lappin TR

更新日期：1981-03-01 00:00:00

abstract：:A method combining alizarin red and a modified silver stain for reticulum fibers in tissue sections is described. The method allows precise localization of calcium deposits and crystals in relation to epithelial and interstitial connective tissue elements. The deposits and their spatial relationships are clearly disce...

journal_title：American journal of clinical pathology

authors： Elbadawi A,Musto LA,Lilien OM

更新日期：1981-03-01 00:00:00

abstract：:The cases of five patients who had sinus histiocytosis with massive lymphadenopathy accompanied by osseous involvement by the disease are presented. Four of the five patients were children. The bone lesions were multiple in four cases and solitary in one. The long bones were most commonly involved (three patients); ot...

journal_title：American journal of clinical pathology

authors： Walker PD,Rosai J,Dorfman RF

更新日期：1981-02-01 00:00:00